The most mainstream view among Futurists has been that Daniel 11 up to verse 35 is about the Hellenistic Era, but then 36-45 jumps forward to the End Times and is Antichrist relevant, and then within that is an internal debate on if the "Willful King" who is the subject of those verses is still a King of The North or if the North is a separate entity in verse 40, I was when I held the standard view in the Willful King being separate camp.
I have on this blog broken with Futurist orthodoxy and argued that the Willful King is Augustus Caesar (with the King of the North in verse 40 being Anthony and his Son by Cleopatra who was given the former Seleucid domains). But I've found on YouTube those who brake with the orthodoxy in the opposite direction have been increasing in popularity, most of them still see some connection to the Hellenistic Kingdoms but see it's leap forward to the "End Times" as being more amorphous. But those who reject any connection to the Hellenistic era do exist.
So I've decided to play Devil's Advocate with those types as well as the standard view.
The Seleucid Kingdom is by historians sometimes treated as synonymous with "Syria" the same way Ptolemy is with Egypt, so that's why trying to map any part of this chapter onto the borders of the modern Middle East tends to involve identifying the North with Syria. But at it's greatest extent the Seleucid Empire also controlled almost all of modern Turkey, Iraq and Iran, stretched even into Pakistan and Afghanistan, held sway over Lebanon and Jordan and even for a time of course had Israel.
To the Ancient World a Civilization's Capital City was even more important to understanding it's identity then it is in our modern Cosmopolitan way of thinking. And the Seleucid Kingdom's Capital was Antioch which was still part of Syria during Roman times but in the initial post WWI redrawing of the Middle East was part of Hatay which became a province of Turkey.
When one attempts to trace the royal genealogical legacy of the Seleucid Dynasty beyond when the Seleucid Kingdom proper ended, it very heavily involves the ruling dynasties of regions in modern Turkey like Pontus, Commagene, Cappadocia, Pergamon, Galatia and Cilicia. Also two of the cities that housed the Seven Churches in Asia of Revelation were founded or renamed by Seleucid Kings, Laodicea and Thyatira, and most of them were part of that kingdom at some point in their history.
Then there is the view of The Little Horn I've been developing, that it never represented an individual per se, in Daniel 8 it's the Seleucid Empire with the bigger horn it came out of being Ptolemy, then in Daniel 7 it's the Eastern Roman Empire/Byzantine Empire which was in many ways the legacy of the Seleucid Empire continued. Then the Ottoman Empire was simply the Byzantine Empire with a change in Religion and Language, and then at the end of WWI what was left of the Ottoman Empire became modern Turkey.
But the Key Argument for the North being Turkey and not Syria in modern geopolitics is the very word "North" itself. In the Hellenistic Context why was the Seleucid Kingdom the North when it wasn't actually the most northern since there were rivals based in both Macedon and Thrace?
It's because the Hebrew word translated "North" here is Zaphon which was also the Semitic name of a mountain the Greeks and Romans called Kasios/Casius but is today called Jebel Aqra/Acra. This mountain was just south of the city of Antioch and Seleucus I Nicator decided to found Antioch where he did after performing a Sacrifice to Zeus on that mountain, at least that was the city's official founding myth.
Today it is officially right on the Syria-Turkey border, but due to Turkey's involvement in the Syrian Civil War it's functionally all under Turkish control. But also just think about it poetically, the Mountain Named "North" is the Sothern most tip of Turkey. For the small group who want to throw the Hellenistic Kingdoms out of how to interpret Daniel 11 entirely, this mountain is the only clue we have and it favors Turkey.
And yes the word for "South" in this chapter is also the name of a specific Geographical location, the Negev Desert which was under Ptolemaic Control when the wars between the Ptolemies and Seleucids that Daniel 11 is talking about started. I think the Ancient definition of the Negev was a bit broader then how it's properly defined today and might have overlapped with The Sinai to include places like Ras Kouroun and so was to some extent still Ptolemaic even after the Seleucids took Judea/Jerusalem.