I have come to view The Woman of Revelation 12, the Harlot of Revelation 17, The Bride of Christ in Revelation 19 and The Lamb's Wife in Revelation 21 as the same Symbolic Woman. I'd stated that on this Blog before but I feel it needs restating, most posts I've done before on any of these personages are pieces in putting this puzzle together.
Most theologians who would say something like this are not Futurists like I am but more taking an Idealist view of Revelation like Peter Heitt. Pre-Trib/PreWrath Dispensationalists tend to view there as being three women (everyone agrees that the Bride and the Wife at the same), while Post-Trib Futurists prefer to see the Bride and the Mother in Revelation 12 as the same but the Harlot as still an irredeemable enemy who simply dies when she is killed.
I believe in Universal Salvation, the Metanarrative of Scripture is that Israel was Widowed and Divorced because of her Adulatorous Harlotry but YHWH is going to Redeem and Remarry her just like Hosea and Gomer, He will Restore Judah and Samaria and even Sodom as Ezekiel 16 clearly states, Ezekiel 27 returns to those themes, this cycle was first laid out in Deuteronomy 29-30 and is reaffirmed in Malachi chapter 3 and Romans 11.
The Dispensationalist view on the Women of Revelation happens to resemble The Three Faces of Eve Trope, which is an analysis of the concept that Patriarchal Society tends to see women in only 3 roles, a faithful Wife/Mother, a Harlotrous Seductress, or a Innocent Virgin/Child. Of course my making all three the same woman can also be seen as an example of that trope. Except that usually as stages in the character development of one character it goes in the opposite direction, you start as an innocent, then get sexually active, then settle down, The Woman of Revelation is introduced giving birth and ends the story as a Virgin.
As an Anime Weirdo, this reading of the Book of Revelation factors into why a number of my favorite Anime are shows where one of the principal Villains is also the Damsel in Distress at the same time, stories where saving the Villainess is the Heroes' emotionally most important objective, the World being Saved in the process is just an added bonus, like how Ezekiel 16 frames the restoration of Sodom as being because it'd be unfair to save Israel but not Sodom, and Roman 11 clarified that it's not till the FULLNESS of the Gentiles are grafted into Israel that ALL Israel shall be Saved.
Pretear and a number of other Magical Girl stories fit this to varying degrees. SSSS.Gridman was one of the shows that first made me see this as a common theme. It's also a big part of Robotics;Notes and Chaos;Child, one could debatably see Utena and Princess Tutu as fitting too. Oh and Future Diary counts as well, but be warned that one is an edgy and trashy ride to get there. [Update April 2023: Now that I've finally watched it I can add Re:Creators to this list.]
It would naturally spoil these shows a bit to go into detail, maybe you feel I've spoiled them by mentioning they do this at all, but I didn't say which characters this applied to. And SSSS.Gridman is a show that isn't good because anything was a surprise, if you're at all Genre Savvy it was clear from episode 1 where it was going. In Robotics;Notes it is also clear early on to the audience that Misaki Senomiya has become a villain in the present, how and why is the mystery. It's Misaki who perhaps best fits the relevance here, she's the older sister of the Female Protagonist and informally basically of the Male Protagonist as well, which is similar to being a mother.
I'm sure there are stories that do this with a male character as well if you want to see these Gender norms subverted, it's just Anime Girls are who I'm most drawn to personally.
These are often exactly the Anime that lend themselves to Bring Me To Life AMVs.
But I should mention in some of these shows the character in questions is not the only villain or even only major villain, there sometimes still is an Unrepentant Pure Evil Antagonist that an infernalsit viewer could view as representing the Reprobate or Satan.